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Real Reason Behind Mike Tyson’s First Boxing Loss Revealed After

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Mike Tyson Buster Douglas

Real Medical Reason Behind Mike Tyson’s First Boxing Loss Revealed After 36 Years

In February 1990, the boxing world witnessed what many still call the biggest upset in the sport’s history. Billed as Mike Tyson’s comeback fight, ‘Buster’ Douglas defied odds and shocked the world by knocking out the youngest heavyweight champion ever in the 10th round. Fans were left stunned, trying to understand what caused Tyson’s stunning collapse. Now, 36 years later, a new layer of truth has surfaced about that historic night.

According to reports, the former heavyweight champion was suffering from the bacterial s***ly transmitted disease gonorrhea, which severely affected his performance. Tyson was reportedly taking heavy doses of prescribed medication, which slowed him down inside the ring. That physical setback allowed Douglas to land the finishing blow, taking away Tyson’s undefeated record along with his WBA, WBC, and IBF heavyweight titles.

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Mike Tyson fought Buster Douglas while battling gonorrhea

“Douglas fought the fight of his life, and Mike fought the worst fight of his life, and got clobbered. It wasn’t until later that I learned of the medical challenges Mike was dealing with,” Dr. Elias Graham, the chairman of the Nevada Athletic Commission, told the New York Post in a recent interview.

Mike Tyson stepping into the ring while dealing with such a serious condition was undeniably brave. But the revelation goes even deeper. ‘Iron Mike’ had actually been suffering from the infection long before the Douglas fight.

According to a 2011 CBS article, Tyson was dealing with the same issue when he defeated Trevor Berbick on November 22, 1986. Describing his experience with the disease, Tyson later spoke about how badly it affected him, as he revealed dripping pus from his genitals.

“I was dripping like a good humid July, man,” the now 59-year-old said, as per the CBS article.

It was a brutally honest and somewhat graphic description from the heavyweight legend. Still, even after gonorrhea was revealed as his hidden kryptonite, Tyson never used it as an excuse.

‘Iron’ lauded Douglas for his performance 

For a dominant champion like Mike Tyson, losing to a massive underdog was always going to sting. But even in defeat, ‘Iron Mike’ showed the mindset of a true champion. When ‘Buster’ Douglas shocked him at the Tokyo Dome in Japan, Tyson accepted the loss with honesty and gave full credit to his opponent for delivering a masterclass.

“Because I took some f–in shots. You know… nobody would have took them shots. It’s just a bang. He fought a great fight that night. What a great fight. But you know what’s so ironic that he won, everybody that beat him, I knocked out,” Tyson stated in an interview with American rapper Joe Budden in 2023.

After that loss, the heavyweight legend went on to regain the WBA and WBC championships, proving he was far from finished. Still, boxing fans continue to regret never seeing a rematch between Tyson and Douglas. It remains one of the sport’s most fascinating what-ifs.

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BOXING

How Mike Tyson Flattening Floyd Mayweather Would Be a Boxing

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Mike Tyson Floyd Mayweather

Mike Tyson Flattening Floyd Mayweather Would Be a Boxing Disaster

An image of Mike Tyson flattening Floyd Mayweather would travel instantly. It would also leave a lasting mark on one of boxing’s cleanest legacies.

But even at 59 and 49, a Tyson knockout of Mayweather in Africa this March would not play as nostalgia. It would read as a business decision that went too far, putting a hole in a record that has been protected for decades for the cold, hard dollar.

Illustrated image of Mike Tyson and Floyd Mayweather in a fictional boxing knockout scene

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Nothing about that outcome does anyone any good.

Mayweather’s brand was built on control
Mayweather’s legacy rests on calculation, preservation, and perfection: fifty wins, no losses, and a career shaped around denying opponents a defining moment.

That is why this kind of exhibition carries a different type of risk. If Mayweather hits the canvas, the debate will not center on rules or labels.

It will become a question of judgment: why one of the sharpest operators in boxing chose to expose his résumé to a heavyweight, long after his own competitive window closed.

A payday is easy to understand. The part that is harder to justify is the trade-off if the visuals turn against him.

The weight gap signals what the event is supposed to be
Mayweather agreeing to give away so much weight to Tyson is not a subtle detail. It suggests the contest is designed to look dangerous without becoming just that, a controlled night that resembles a glorified sparring session more than a real fight.

That is also why a knockout becomes the nightmare scenario. It would mean the one man expected to manage the pace and shape the evening could not.

If Tyson decides to go for it, the night can turn ugly
Tyson’s performance against Jake Paul suggested restraint and an understanding of the assignment. If the same approach carries into an exhibition, the event remains what it is intended to be: entertainment, contained and forgettable.

But if Tyson took it upon himself to go for it, the exhibition label would not protect anyone. The moment the illusion breaks, the fight stops being a curiosity and becomes a controversy.

In the worst case, it could carry the same kind of fallout Tyson created against Evander Holyfield, when spectacle crossed into something boxing could not comfortably explain away.

A Tyson knockout would not elevate the Baddest Man. It would not enhance Mayweather. It would not help boxing.

It would turn a carefully managed legacy into a clip, by choice, and not by necessity.

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BOXING

Why Floyd Mayweather Prefers Secrecy as Tyson and Pacquiao Le

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Floyd Mayweather Mike Tyson Manny Pacquiao

Floyd Mayweather Prefers Secrecy as Tyson and Pacquiao Leak Fight Plans

Fighters don’t just lose matches — sometimes they lose the narrative. That may be what Floyd Mayweather is thinking after two of his biggest rivals — Mike Tyson and Manny Pacquiao — publicly revealed details about future match-ups.

Mayweather vs Tyson Africa poster

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Tyson Drops the Bomb
At his “An Evening With Mike Tyson” event this week, Tyson stunned the audience by leaking plans when asked who his next fight would be against.

“Floyd Mayweather, can you believe that? It’s going to be in March in Africa. It’s going to break all the records.”

That revelation adds fresh heat to one of boxing’s most talked-about exhibitions: Tyson vs. Mayweather, expected in March 2026 somewhere on that continent.

Mayweather Likes to Control the Narrative
Mayweather built his 50‑0 professional legacy across five weight divisions by meticulously controlling timing, promotion, and media narratives.

So when Tyson — a man who once called Mayweather “a little scared man” for comparing himself to legends — announced the fight details in front of fans, he didn’t just hype the event. He encroached on Mayweather’s turf.

Pacquiao Set the Precedent
It isn’t the first time someone spilled what Mayweather preferred to keep under wraps. Earlier this year, Pacquiao revealed details of a planned 2026 rematch.

A few weeks after confirming it, he cut off a reporter who asked about the fight during his son’s professional debut in Los Angeles.

Observers noted Mayweather likely would have told Pacquiao to stay quiet — the same principle that makes Tyson’s public reveal potentially irritating for Floyd.

The Stakes Behind the Scenes
Now that Tyson is doing the same, the pattern is clear: the spectacle may thrill fans, but behind the scenes, Mayweather’s preference for control is being challenged.

Come March, Africa will host a historic exhibition that’s sure to break records — but behind the cameras, the real fight is already in motion.

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BOXING

How Mike Tyson set a record that no one has come close to when h

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Mike Tyson

Mike Tyson set a record that no one has come close to when he steamrolled Muhammad Ali’s last foe

In 1986, Mike Tyson won his first heavyweight title in just two rounds.

Tyson claimed that he was scared “to death” ahead of his boxing debut back in March of 1985 at the Plaza Convention Center in Albany, New York.

Fortunately for him, this fight would establish his trademark, with the 18-year-old needing just 107 seconds to put Hector Mercedes away.

Mike Tyson stuns Trevor Berbick in their 1986 WBC heavyweight title fight

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Tyson produced many statement knockouts in his career, recording a total of 44 knockouts in 50 career wins from 1985 to 2005, before he returned last year to face Jake Paul.

However, it was the finish that ‘Iron Mike’ produced on November 22 of 1986 that saw his name instantly enter boxing’s history books.

Mike Tyson is still the youngest ever heavyweight champion after beating Trevor Berbick in 1986

After making his debut at 18 years old, Mike Tyson, largely thanks to his ability to end fights very quickly, racked up lots of pro wins in a short space of time.

Despite going the distance multiple times in 1986, his second year as a pro also saw Tyson produce his quickest knockout win and claim his first world title in spectacular fashion.

His 13th fight of the year saw ‘Kid Dynamite’ challenge the 32-year-old WBC heavyweight champion Trevor Berbick in Las Vegas.

The experience of Berbick proved to be no match for his opponent’s ferocious power and aggression, as Tyson claimed the belt with a TKO in the second round.

This made him boxing’s youngest heavyweight world champion at 20 years old, a record that still stands today.

He climbed above Floyd Patterson and Muhammad Ali, who fought each other on two occasions, in order to top the list.

Youngest boxing heavyweight champions Date Age
Mike Tyson November 22, 1986 20 years, 4 months, 23 days
Floyd Patterson November 30, 1956 21 years, 10 months, 26 days
Muhammad Ali February 25, 1964 22 years, 8 days
Joe Louis June 22, 1937 23 years, 1 month, 9 days
Jack Dempsey July 4, 1919 24 years, 0 months, 10 days
George Foreman February 22, 1973 24 years, 0 months, 12 days
Joe Frazier March 4, 1968 24 years, 1 month, 21 days
James J. Jefferies June 9, 1899 24 years, 1 month, 25 days
Michael Dokes December 10, 1982 24 years, 6 months
Wladimir Klitschko October 14, 2000 24 years, 6 months, 19 days

The only fighter to have made it onto the list since Tyson broke the record is Wladimir Klitschko.

The Ukrainian’s second-longest heavyweight title reign of all time at 4,382 days (combined) started when he was nearly four years older than ‘Iron Mike’, beating Chris Byrd in 2000 for the WBO belt.

A new youngest active world champion was crowned earlier this year

While Mike Tyson may be the youngest heavyweight champion of all time, he doesn’t come close to the record for the youngest champion regardless of weight class.

That honor goes to Wilfred Benitez, who in March of 1976, defeated Antonio Cervantes via split decision to win the WBA and The Ring light welterweight titles at just 17 years old.

The accolade for being the youngest active world champion changed hands earlier this year when 22-year-old Xander Zayas won the WBO light middleweight belt from Jorge Garcia Perez.

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BOXING

Why Jake Paul blamed Mike Tyson for disappointing Netflix dud th

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Jake Paul Mike Tyson

Why Jake Paul blamed Mike Tyson for disappointing Netflix dud that 60 million households tuned in for

Netflix entered the world of combat sports with a controversial fight one year ago today.

The global streaming platform staged its first live boxing event on November 15, 2024, and they chose a polarizing matchup to kick things off.

Mike Tyson throws a punch at Jake Paul during their Netflix fight

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Jake Paul beat Mike Tyson on Netflix, with the former Disney star having his hand raised over an opponent two decades older than him at AT&T Stadium in Arlington, Texas.

The age gap between the YouTuber-turned-boxer and the ex-heavyweight world champion caused plenty of backlash in the lead-up to the fight. But that did not stop 59,666 people from securing tickets and 60 million households from tuning in live.

Most were left disappointed, however, after fears over Tyson’s physical condition became a reality as he struggled to put on much of a fight against ‘The Problem Child’.

Jake Paul said it was Mike Tyson’s fault he couldn’t ‘put on a show’ in their controversial Netflix fight

Given the wave of criticism directed at Jake Paul for opting to fight a 59-year-old boxing veteran, it was no surprise to see that only grow after how the bout unfolded.

UFC legend Don Frye said Paul vs. Tyson made him want to “vomit,” and he was not the only prominent name calling out the Cleveland native and Netflix for putting it on. Others, meanwhile, were hoping for a more entertaining affair.

Speaking at the post-fight press conference, Paul addressed those who were left frustrated by the lackluster contest, insisting that he planned to put on more of a show but was limited by Tyson’s struggle to make it through the match.

“I wanted to give the fans a show, but I didn’t want to hurt someone that didn’t need to be hurt,” Paul said.

“I tried to give the best fight I possibly could, but when someone’s just surviving in the ring, basically it’s hard to make it exciting.

“So I couldn’t really get him to engage me or slip shots and do something super cool or whatever,” he added.

Mike Tyson vows to knock out Floyd Mayweather in 2026

Against the wishes of many of his fans and boxing peers, Tyson doesn’t appear to be done in the ring.

59-year-old Tyson is planning to face Floyd Mayweather in 2026. While an exact date remains unconfirmed, the pair announced a controversial exhibition grudge match back in September.

‘Iron Mike’ is promising an improved performance and even recently vowed to knock out the retired 50-0 star.

“It looks that way, as I anticipated. It looks like he’s (Mayweather) going to get knocked out,” Tyson told Hard Rock Bets during a recent interview.

“It’s [the fight] going to supersede all the fights and all the glory he had before this. This is taking boxing to a new level. Almost ‘God status’,” he added.

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‘Drives me crazy’ – Mike Tyson opens up on ‘really bad’ secret health condition

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Mike Tyson

Mike Tyson insists a severe case of foot fungus is “kicking his a***”.

The former undisputed heavyweight champion had been suffering from the infection in silence, but opened up about his struggles during a Tuesday night taping of Jimmy Kimmel Live.

Kimmel picked up on the fact that Tyson never wears socks and so asked him why.

“I only used to [not wear socks] for fighting, where that was my image,” Tyson replied.

Mike Tyson fights during LIVE On Netflix: Jake Paul vs. Mike Tyson at AT&T Stadium on November 15, 2024 in Arlington, Texas

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“It was real hardcore, no socks. Then I discovered I had a very disintegrating dose of foot fungus.

“And it was really bad. It’s still really bad now.”

Kimmel then quipped: “Would you say that foot fungus is your greatest opponent of all?”

To which, Tyson joked: “Well, I would have to say so because it’s still kicking my a*** now.”

Foot fungus can traditionally be treated with creams, sprays and powders from a pharmacy.

However, Tyson insists he has tried these methods to no avail.

“Desenex cannot help me,” added Tyson. “My toes look like they blew up.”

Mike Tyson slapped Jake Paul after stepping on his toes

During the final face-off for his comeback fight with Jake Paul last November, Tyson slapped the YouTuber-turned-boxer after he stepped on his toes.

Tyson slapped Paul during their face-off on Thursday as tempers flared

There appeared to be minimal contact from Paul, but Tyson’s latest admission explains why he flipped out.

“I was in my socks and he had on shoes,” Tyson told The Post moments after the weigh-in.

“He stepped on my toe because he is a f****** a***hole. I wanted to think it happened by accident.

“But now I think it may have happened on purpose. I was in a lot of pain. I had to reciprocate.”

Will Mike Tyson box again?

Boxing fans had hoped that Tyson’s bout with Paul would be his last.

However, the 59-year-old has since announced an upcoming exhibition bout with Floyd Mayweather.

Despite the shock-factor, Mayweather vs Tyson is anticipated to bring in huge numbers

Details on the exact date and venue were not confirmed, although it has been earmarked for Spring 2026.

Las Vegas and Saudi Arabia are said to be the potential locations in the running, with CSI Sports/Fight Sports set to stage the event.

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How Floyd Mayweather vs Manny Pacquiao II leaves Mike Tyson fight in jeopardy as

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Floyd Mayweather Manny Pacquiao Mike Tyson

Floyd Mayweather vs Manny Pacquiao II leaves Mike Tyson fight in jeopardy as target date revealed

A rematch between Floyd Mayweather and Manny Pacquiao is set to clash with ‘TBE’s’ proposed exhibition bout against Mike Tyson.

In early September, Mayweather announced that he will lock horns with the former undisputed heavyweight champion next spring.

The exact details were scarce, with no date, location, or catchweight confirmed for the two combatants who are separated by more than 80lbs.

Iron Mike Tyson weighs in on Mayweather-Pacquiao fight | FOX Sports

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And it is now unclear where the fight stands after Mayweather and Pacquiao entered into talks over a rematch, 10 years after meeting in the most commercially successful contest in boxing history.

According to esteemed boxing journalist Dan Rafael, the bout is being targeted for April in Las Vegas, leaving Tyson-Mayweather in a precarious position.

If Mayweather-Pacquiao II goes ahead as planned, then organisers will either have to push back the Tyson fight or scrap it altogether.

What has Manny Pacquiao had to say about a rematch with Floyd Mayweather?

Pacquiao recently confirmed that he and Mayweather are thrashing out the details for a second fight.

Speaking to The Sun, he said: “As long as Floyd will come back. I’m active in boxing, it’s possible.”

“There is a talk. Like I said, I’m happy to start talking about, discussing about a possible rematch with Floyd.

“Of course, there’s a good chance to have a rematch because I’m still active – it’s only if he will come back that’s possible.”

It has yet to be agreed whether the bout would be an exhibition bout or a professional contest, although ‘Pac Man’ has made it clear he wants the sequel to be a ‘real fight’.

“I don’t know if it will happen by the end of the year, but he will see,” Pacquiao told the Ariel Helwani Show in July when talks of a rematch initially emerged.

“One at a time. Of course [I would be interested in fighting Mayweather].

“He has been ducking me. I don’t want an exhibition, I want a real fight.

“It’s been a long time that I have wanted to give the fans a good fight between me and him.

“But he has been ducking and avoiding me. Let’s focus on this Saturday, I have business to take care of.”

Pacquiao, 46, shocked the boxing world in July when he returned to the professional ring for the first time in four years to hold WBC welterweight champion Mario Barrios to a draw.

Mayweather, 48, hasn’t competed in the paid ranks since August 2017, but he has remained active in the exhibition boxing sphere.

What happened the last time Floyd Mayweather and Manny Pacquiao met?

The American icon beat Pacquiao comfortably on points when they met for the first time in May 2015 at Las Vegas’ MGM Grand Garden Arena.

However, Pacquiao claims he tore his rotator cuff in sparring a month before their inaugural encounter and was denied anti-inflammatory shots.

He added: “I’ve been motivated since after the fight.

“After the operation, I was OK to get back in the ring and fight again.

“Right now, God is good and giving me strength and good health to continue my career as a boxer.”

Pacquiao has been chomping at the bit to exact his revenge ever since.

“I’m a fighter as well. I’m not ducking anybody. I can fight anybody,” he continued.

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Watch The KO that proved Mike Tyson was a different beast

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Mike Tyson

Boxing legend Mike Tyson was at his ruthless best on October 16, 1987.

The 31-0 knockout artist had already established himself as the best heavyweight on the planet.

Mike Tyson appeared to have his work cut out for him when he put the WBC, WBA, and IBF titles on the line against a 15-0 contender.

Mike Tyson vs Tyrell Biggs | October 16, 1987 | Highlights HD 60[fps]

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Tyrell Biggs stood at 6ft 5in tall and had the skills to potentially cause some problems. Good movement and a solid jab were two of the reasons he was able to win super heavyweight gold at the 1984 Olympics.

Watch Mike Tyson destroy Tyrell Biggs

Tyrell Biggs used his frame and footwork to keep Mike Tyson at bay for the first two rounds, but it was all downhill from there.

From round three on, the undisputed heavyweight champion began effectively cutting off the ring and landing big punches, which left Biggs’ face a swollen mess.

In round 7, Tyson sent his opponent crashing through the ropes with a monstrous left hook. Biggs was bloody and dazed, but he managed to make it back to his feet at the count of nine.

Tyson immediately landed a massive overhand right when the fight recommenced. Biggs tried to hold on, but the 21-year-old superstar landed another left hook to end the fight.

Biggs went flying across the ring into the corner, where the referee stood over him and waved off the fight with just one second left in the seventh stanza.

Mike Tyson’s next fight

Mike Tyson retired from professional boxing after suffering a stoppage loss to Kevin McBride in 2005.

Almost two decades later, the 59-year-old shocked the world by announcing a professional boxing comeback.

Tyson looked like a shadow of his former self but still managed to go the distance with Jake Paul in November 2024.

Next up, Tyson is set to face Floyd Mayweather in an exhibition mismatch scheduled for 2026.

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Why Mike Tyson is motivated to ‘do better’ against Floyd Mayweath

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Mike Tyson Floyd Mayweather

Mike Tyson is motivated to ‘do better’ against Floyd Mayweather

Mike Tyson is preparing for one of the most unexpected fights in modern boxing history — showdown clash with Floyd Mayweather next spring. As the 59-year-old legend steps back into the ring spotlight, he’s taking lessons from his recent defeat to Jake Paul.

“I couldn’t believe it until he signed,” Tyson said of Mayweather’s confirmation. “He signed it, so I believe it.”

Mike Tyson is motivated to ‘do better’ against Floyd Mayweather

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Looking back on his loss to Jake Paul, Tyson said the most important lesson wasn’t about physical preparation but mental focus. “I wasn’t as focused as I should have been,” he admitted. “This moment’s going to be over. Just enjoy it — it doesn’t last forever.”

Now, as he trains for his much-anticipated clash with Mayweather, Tyson says his motivation comes from gratitude rather than rivalry. “I’m just preparing and looking forward,” he said. “It’s a wonderful thing that could happen.”

Tyson described the fight as “something neither the world nor I ever thought would or could happen,” calling it part of “a new era of the unpredictable” in boxing.

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Mike Tyson Makes Promise Ahead of Floyd Mayweather Fight

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Mike Tyson Floyd Mayweather

Mike Tyson has warned Floyd Mayweather yet again about their upcoming fight in 2026. ‘Iron’ Mike, now 59, is coming back to take on Mayweather in 2026 in an exhibition bout.

It’s a clash of two legends. Tyson is arguably the biggest name in the history of boxing while 50-0-0 Mayweather is the sport’s most profitable superstar to date. And there’s no doubt fans will tune in when two greats of their respective eras share the ring next year.

Tyson lost to Jake Paul via unanimous decision in November 2024. At 58, Tyson looked like a man of his age, but he’s made a promise about the Mayweather fight that might sound like a warning music to the latter’s ears.

Mike Tyson Floyd Mayweather

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Mike Tyson speaks out on Floyd Mayweather bout

Tyson has promised he’d be better than his last bout against ‘The Problem Child’. Speaking to People, he said, “It’s going to be really interesting. I can’t believe, since the last time I did this, I’ve fought… What? Two times, going on three times…I’ll do better in the next one.”

While Tyson is now 59, he is a special type of human being. And if he promises to improve, any opponent, even if that’s Mayweather, needs to take note. Tyson is also looking to live in the moment for the upcoming fight. He said:

“This moment’s going to be over. Just enjoy it, it doesn’t last forever.”

– Mike Tyson

Tyson retired from professional boxing in 2005. He returned inside the ring in 2020 to take on Roy Jones Jr in an exhibition. In 2024, his bout against Paul was under professional settings. The Mayweather clash, though, will be an exhibition.

As for ‘Money’ Mayweather, his last professional outing was in 2017, a 10th round TKO win against UFC icon Conor McGregor. Mayweather has since appeared in exhibition bouts, taking on Tenshin Nasukawa, Logan Paul, Deji, and more.

Tyson ruled the heavyweight division during his career while Mayweather is the king of lighter weight classes. Neither is in their prime, meaning fans can expect a showcase of their skills in this spectacle instead of an actual fight. With two legends like them involved, it can be expected to be a show stopping event regardless of all the aforementioned factors.

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